Agenda

8:30 – 9:00
Registration and Breakfast
9:00 – 9:10
Welcome and Introduction
CANCER GENOMICS
Chair: Lillian Siu, MD, Princess Margaret Cancer Centre
9:10 – 10:00
KEYNOTE: Clinical Applications of High Throughput Sequencing-Based Circulating Tumor DNA Analysis
Max Diehn, MD, PhD, Stanford University
10:00 – 10:30
Precision Oncology for Young People (PROFYLE) Program
Meredith Irwin, MD, Hospital for Sick Children
10:30 – 10:45
Break
10:45 – 11:15
Update on the Cancer Genomics Program at Princess Margaret
Philippe Bedard, MD, and Trevor Pugh, PhD, Princess Margaret Cancer Centre
11:15 – 11:45
Immunogenomics as a Tool to Guide Rational Drug Development and Clinical Care
Adrian Sacher, MD, Herbert Irving Comprehensive Cancer Center
11:45 – 12:00
Panel Discussion
12:00 – 12:30
Lunch
TUMOR IMMUNOTHERAPY
Chair: Pamela Ohashi, PhD, Princess Margaret Cancer Centre
12:30 – 1:20
KEYNOTE: Anti-CD19 CAR-T Cell Therapy for Aggressive B Cell Lymphoma: Zuma-1 and the Moffitt Experience
Frederick Locke, MD, Moffitt Cancer Center
1:20 – 1:50
The Impact of Tumor Microenvironment on Immune Response in Triple Negative Breast Cancer
Morag Park, PhD, McGill University
1:50 – 2:05
Break
2:05 – 2:35
Mechanisms of T Cell Exhaustion
Pamela L. Schwartzberg, MD, PhD, National Human Genome Research Institute
2:35 – 3:05
Unexpected T Cells Recognizing Tumour Associated Antigens
Juan Carlos Zúñiga-Pflücker, PhD, Sunnybrook Research Institute
3:05 – 3:20
Panel Discussion
3:20 – 3:30
Closing Remarks
Lillian Siu, MD, Princess Margaret Cancer Centre